University of North Carolina at Chapel Hill
Development of Catalytic Stereoselective Nucelophilic Addition Reactions for Organic Synthesis
This seminar will focus on our recent progress in developing new catalysts and strategies for chemical synthesis. Our group has a long-term interest in developing catalyst-controlled nucleophile addition processes that enable new approaches to stereoselective C–C bond construction. In this regard, the development of catalytic enantioselective reactions of boron-stabilized alkylmetals will be discussed. In addition, the design and development of electrophilic carbon(0) ligated rhodium(I) complexes for catalytic site- and enantioselective hydrofunctionalizations of olefins will be presented.