Naoya Kumagai

Microbial Chemistry Research Foundation
Institute of Microbial Chemistry, Tokyo
Wednesday, Feb. 28, 2018 4:30pm
Edward C. Taylor Auditorium, Frick B02
Todd Hyster
Add to Calendar2018-02-28 16:30:002018-02-28 16:30:00Todd HysterEdward C. Taylor Auditorium, Frick B0215YYYY-MM-DD

Reaction Development in the Amide Playground

I will deliver 4 topics on the amide functionality;

  1. Direct enolization chemistry of amide via designed asymmetric cooperative catalytic system.[JACS 2015, 137, 15929, etc.]
  2. Utility of asymmetric amide-based ligand for asymmetric flow catalysis.[ACIE 2013, 52, 6196, etc.]
  3. Catalytic direct dehydrative amidation by a novel B3NO2 heterocyclic catalyst.[Nature Chem. doi:10.1038/nchem2708, etc.]
  4. Twisting amide planarity: structural study and reactivity.[Chem. Sci. 2017, 8, 85, etc.]

These issues will be discussed with emphasis on synthetic utility and reaction mechanisms.