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Veronique Gouverneur

Seminar
Fri, Nov. 14, 2014, 4:30pm - 6:00pm
Frick Chemistry Laboratory, Taylor Auditorium
Host: Abby Doyle

Speaker Details:

Veronique Gouverneur

Chemistry Research Laboratory
University of Oxford

Gouverneur Group

Research Area:

Catalysis / Synthesis

Fluorine Chemistry: Basic to Clinic

The beneficial influence of fluorine substitution is unquestionable in drug discovery. Numerous fluorine-containing sub-motifs are employed, each fulfilling a distinct function to improve drug efficacy. It is reasonable to anticipate that structural diversity in 18F-tagging could also have a positive impact on radiotracer’s development for Positron Emission Tomography imaging. This lecture will discuss how we are intending to expand the range of 18F-tags for labeling, with radiochemistry inspired from the various synthetic catalytic manifolds exploited for late stage fluoro- functionalization.