Arkadi Vigalok

Organometallic Fluorine Chemistry: New Reactions and Mechanisms

Organometallic fluorine chemistry has received considerable attention during the last decade. Particularly, electrophilic fluorination of organometallic platinum group complexes has emerged as a powerful tool to introduce various functions into organic compounds.¹ In this talk, I will present our results on the formation of C-C, C-X (X= F, I) and I-F bonds under the electrophilic fluorination conditions. I will also discuss mechanistic requirements for the reductive elimination of carbon-halogen bonds taking place under the kinetic conditions.

In the second part of my talk, I will present our latest studies of the new pincer ligand system bearing fluorine atom as a side arm. In particular, I will discuss the reactions leading to stoichiometric and catalytic activation of O-H, N-H, S-H and C-H bonds that involve reversible dearomatization-aromatization of the ligand’s aromatic core.² 

References:

1. Vigalok, A. Acc. Chem. Res. 2015, 48, 238-247

2. Scharf, A.; Goldberg, I.; Vigalok, A. J. Am. Chem. Soc. 2013, 135, 967−970