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Kenneth Fraunhoffer

Kenneth Fraunhoffer

Student Invited Lecture
Wed, Sep. 30, 2015, 4:30pm
Frick Chemistry Laboratory, Taylor Auditorium
Host: Derek Ahneman (GSO)
Speaker Details:
Kenneth Fraunhoffer

Senior Research Investigator II-Early Phase Chemical Development Group
Bristol-Myers Squibb

Research Area:

Process Chemistry in the Pharmaceutical Industry: Concepts and Selected Examples

Process chemistry, the development of novel, scalable, and cost-effective routes to drug candidates, is a central component of the pharmaceutical industry.  This talk will provide a general overview of process chemistry and detail two case studies from the Bristol-Myers Squibb portfolio.  Highlights of the case studies include discovery of a chemo- and diastereoselective reductive amination using ammonia and hydrogen and development of a complex four step reaction sequence demonstrated at manufacturing scale.