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Stavroula Hatzios

Chemical Tools for Uncovering New Redox Biology at the Host–Microbe Interface

Thu, Apr. 25, 2024, 4:30pm
Taylor Auditorium, Frick Chemistry Lab B02
Host: Ralph Kleiner

Abstract:

My lab studies host–microbe interactions in the gastrointestinal tract by using chemical tools to discover proteins, post-translational modifications, and metabolites that shape cell signaling at the molecular level. Our primary goal is to understand how infection-associated oxidative stress influences host cell signaling and microbial adaptation to the host environment. In this talk, I will present some of our recent work using reactivity-guided approaches to uncover proteins, metabolites, and metabolic pathways that shape cellular responses to oxidative stress at the host–microbe interface.