Fri, Feb. 10, 2017, 4:30pm - 6:00pm
Frick Chemistry Laboratory, Taylor Auditorium
Host: David MacMillan
ASYMMETRIC HYDROFUNCTIONALIZATION OF ALKENES
The availability of a general method for the catalytic conversion of olefins into enantiomerically enriched amines has eluded chemists for decades. We have recently developed a simple copper-catalyzed method to effect such a transformation. This lecture will describe our progress, applications of our methodology as well as our current view of the mechanism of the hydroamination process. In addition, we will describe our progress in developing new methods for carbon-carbon bond formation that utilize alkyl copper intermediates.