Tim Newhouse
Tim Newhouse
Seminar
Thu, Oct. 11, 2018, 4:30pm
Edward C Taylor Auditorium, Frick B02
Host: Todd Hyster
Thu, Oct. 11, 2018, 4:30pm
Edward C Taylor Auditorium, Frick B02
Host: Todd Hyster
The 2018 Millipore Sigma Lecture
Computationally Guided Total Synthesis of Neuroactive Terpenoids
![](https://chemistry.princeton.edu/wp-content/uploads/drupal/event-images/tim-newhouse-ai-enlarged.jpg)
This talk will describe the total synthesis of neurologically active terpenoid natural products using novel strategies and methodologies for step-efficient syntheses. Methodological developments in the area of allyl-palladium catalysis will be described in detail that have allowed for alpha,beta-dehydrogenation of a variety of carbonyl compounds. Unique strategies and key retrosynthetic disconnections are guided by computational investigation.